A case of seborrheic blepharitis; treatment with itraconazole.
نویسندگان
چکیده
We report a case of seborrheic blepharitis treated with oral itraconazole during a short period. Direct examination using Parker KOH revealed numerous hyphae and spores of Malassezia in the scale. Low-dose itraconazole pulse therapy (200 mg daily, 7 days a month) was quite effective. This is the second case in which we also observed a unique fungal conformation which looked like tinea versicolor. The evidence strongly suggests that Malassezia is one of the major causative agents of seborrheic blepharitis.
منابع مشابه
Investigations of seborrheic dermatitis. Part II. Influence of itraconazole on the clinical condition and the level of selected cytokines in seborrheic dermatitis.
INTRODUCTION The pathogenesis of seborrheic dermatitis has not been fully elucidated. A number of anascogenic yeasts of Malassezia spp. appear to be involved in the intensity of the symptoms. The purpose of the study is to evaluate the levels of selected inflammatory cytokines, IL-2, IL-4, IFN-γ and TNF-α, in the serum after treatment with itraconazole. MATERIAL/METHODS Sixty-six subjects wer...
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BACKGROUND Seborrheic dermatitis is a common chronic disease. Malassezia yeasts have been implicated in the pathogenesis of this disease. Antifungal agents are known to be effective in the treatment of Malassezia yeast infections. OBJECTIVES To evaluate the efficacy of itraconazole in the treatment of mild to severe facial seborrheic dermatitis. METHODS Sixty patients with moderate to sever...
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متن کاملRF-Itraconazole Pulse Therapy for Seborrheic Dermatitis: A Treatment Approach to Consider.
In our routine clinical practice, seborrheic dermatitis (SD) is a common reason for seeking care. The prevalence of this condition is as high as 5% of the adult population. SD is a chronic and recurrent disease. It is common to see patients who have SD outbreaks with a certain degree of regularity, despite the availability of suitable topical treatment. As a general rule, oral treatment is rese...
متن کاملEffect of itraconazole on the quality of life in patients with moderate to severe seborrheic dermatitis: a randomized, placebo-controlled trial
BACKGROUND Few studies have examined the effect of seborrheic dermatitis (SD) and/or its consequent therapy on a patient's quality of life. Itraconazole has been suggested as an effective therapy for severe SD but its impact on Quality of Life (QoL) in these patients has never been studied before. OBJECTIVE The study aimed to verify the efficacy of the itraconazole on the quality of life in p...
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عنوان ژورنال:
- Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology
دوره 43 3 شماره
صفحات -
تاریخ انتشار 2002